Endocrine Abstracts

I would like to present a case of autoimmune poly glandular syndrome who first presented as profround hypothyroidism and secondary amenorrhea 8 years after her first baby. TSH was >100 and LH and FSH 44.3 and 27 at diagnosis with oestradiol of 18. As patient remained symptomatic after being on thyroxine replacement she went on to undergo a synacthen test which showed a much blunted response (baseline cortisol 264, 30 min 273 and 60 min 264). While being investigated as an ...

Introduction: Osteoporosis poses a significant public health issue, causing significant morbidity and mortality. It leads to an increased fracture risk through a reduction in the bone mineral density (BMD), disruption of bone microarchitecture, and alteration of the amount and variety of non-collagenous proteins in bone. Treatment aims are to prevent fractures and maintain the quality of life of the aging adult. The advent of the WHO assessment tool ‘Fractur...